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Three copper transcript papers still do not create a copper test
The evidence library is allowed to change in public. This page preserves the revised boundary, why it moved and which guides were affected.
What changed
The chemical-safety guide includes a reviewed 2018 pooled whole-body transcript experiment, while 2021 cephalothorax and 2022 hepatopancreas RNA-seq papers remain in the screening queue until their complete methods are available.
Why it changed
The reviewed study does not report exposure vessels, independent vessel replication or the time-series concentration, pools three animals and contains a freshwater-versus-28-PSU inconsistency. The two later publisher previews expose six libraries each but not enough methods to resolve tank replication, sample mapping, full analysis or whether the same laboratory used independent animal cohorts. None validates a diagnosis, safe concentration, whole-animal outcome or biomarker panel.
Sources reviewed for this change
- https://doi.org/10.22438/jeb/39/1/PRN-108
- https://doi.org/10.1016/j.gene.2020.145098
- https://doi.org/10.1016/j.fsi.2021.10.029
Affected practical guides
A public change is not automatically a retraction. A source may be added, a scope narrowed, a gap refined or an error corrected. The current guide and registry record own the current wording.
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