The diclofenac control was not an analytical zero

The evidence library is allowed to change in public. This page preserves the revised boundary, why it moved and which guides were affected.

What changed

The chemical-safety and breeding evidence boundary now reports the measured control concentration, survivor-conditioned later endpoints and the distinction between fewer broods and a statistically significant treatment effect on hatchling count.

Why it changed

The two control checks contained 0.009 and 0.006 mg/L diclofenac, while the nominal 0.1 and 1 mg/L treatments averaged 0.1320 and 1.0730 mg/L. The first egg cohort had partly developed before exposure, later brood samples depended on survival and spawning, and hatchling counts did not differ significantly among treatments. The SSRN and Research Square records are preprint versions of the published study, not independent replication.

Sources reviewed for this change

Affected practical guides

A public change is not automatically a retraction. A source may be added, a scope narrowed, a gap refined or an error corrected. The current guide and registry record own the current wording.

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