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Open nickel data improve denominators without adding dose replication
The evidence library is allowed to change in public. This page preserves the revised boundary, why it moved and which guides were affected.
What changed
The chemical-safety guide now links the two CC BY nickel deposits and distinguishes their numbered samples and quantitative rows from independent replication of the exposure.
Why it changed
The 2024 deposit has three numbered TXRF samples per group but measures whole-shrimp nickel rather than exposure-water concentration. Its reactive-oxygen tables contain uneven rows and repeated dates without independent-animal identifiers. The deposit corresponding to the 2025 article supplies five values per group and organ for mitochondrial potential, ATP and ADP/ATP, but does not link specimens across methods. The two articles remain one research sequence using one high nominal dose scheme.
Sources reviewed for this change
- https://doi.org/10.1080/24750263.2024.2310041
- https://doi.org/10.18150/KEW0KP
- https://doi.org/10.1080/24750263.2025.2533312
- https://doi.org/10.18150/Z04VGN
Affected practical guides
A public change is not automatically a retraction. A source may be added, a scope narrowed, a gap refined or an error corrected. The current guide and registry record own the current wording.
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