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Knowledge gap refined August 11, 2026

A hepatopancreas transcriptome is not an AHPND diagnosis

The evidence library is allowed to change in public. This page preserves the revised boundary, why it moved and which guides were affected.

What changed

The screening queue now includes a 2022 injected Vibrio hepatopancreas RNA-seq paper and separates its transcript comparison and AHPND framing from strain virulence, lesions and whole-animal disease outcomes.

Why it changed

The accessible sources report six libraries, 21,464 differentially expressed genes and eight qPCR checks, but do not expose complete challenge units, pooling or sample mapping. They do not establish that the strain carried PirAB toxins or report shrimp survival, clinical signs, bacterial load, clearance or pathology, so the paper stays full text needed and is not counted as an independent replication of the same group's gill experiment.

Sources reviewed for this change

Affected practical guides

A public change is not automatically a retraction. A source may be added, a scope narrowed, a gap refined or an error corrected. The current guide and registry record own the current wording.

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